Alexander Culley
Regular member
Department of Biochemistry, Microbiology and Bioinformatics
Laval University


Karel Cadoret (Master student)

Valérie Langlois (Ph.D. student)

Thomas Pitot (Ph.D. student)

Juliette Provencher (Master student)

Josephine Rapp (Postdoctoral fellow)


Flora Amill (Ph.D. student)

Recent Theses and Dissertations

Anne-Marie Lapointe (Master - 2022)
Microbial community structure in high Arctic lake sediments

Catherine Marois (Master - 2021)
Characterization of microbial communities in lakes of the Stuckberry Valley in the Canadian High Arctic

Myriam Labbé (Doctorate - 2021)
Viral diversity throughout changing nordic salinity gradients

Scientific Communications

Langlois, V., Girard, C., Vincent, W.F., Culley, A.I., 2023. A Tale of Two Seasons: Distinct Seasonal Viral Communities in a Thermokarst Lake. <strong>Microorganisms</strong>, 11(2), 428. DOI: <a href="" target="_blank">10.3390/microorganisms11020428</a>.

Domínguez-Huerta, G., Zayed, A.A., Wainaina, J.M., Guo, J., Tian, F., Adjie Pratama, A., Bolduc, B., Mohssen, M., Zablocki, O., Pelletier, E., Delage, E., Alberti, A., Aury, J.-M., Carradec, Q., da Silva, C., Labadie, K., Poulain, J., Tara Oceans Coordinators,., Bowler, C., Eveillard, D., Guidi, L., Karsenti, E., Kuhn, J.H., Ogata, H., Kubatko, L.S., Culley, A.I., Chaffron, S., Sullivan, M.B,, 2022. Diversity and ecological footprint of global ocean RNA viruses. <strong>Science</strong>, 376(6598): 1202-1208. DOI: <a href="" target="_blank">10.1126/science.abn6358</a>.

Fradette, M.-S., Culley, A.I., Charette, S.J., 2022. Detection of <em>Cryptosporidium </em>spp. and <em>Giardia </em>spp. in environmental water samples: A journey into the past and new perspectives. <strong>Microorganisms</strong>, 10(6), 1175. DOI: <a href=" " target="_blank">10.3390/microorganisms10061175 </a>.

George, P.B.L., Rossi, F., St-Germain, M.-W., Amato, P., Badard, T., Bergeron, M.G., Boissinot, M., Charette, S.J., Coleman, B.L., Corbeil, J., Culley, A.I., Gaucher, M.-L., Girard, M., Godbout, S., Kirychuk, S., Marette, A., McGeer, A., O'shaughnessy, P., Parmley, E.J., Simard, S., Reid-Smith, R.J., Topp, E., Trudel, L., Yao, M., Brassard, P., Delort, A.-M., Larios, A.D., Létourneau, V., Paquet, V.E., Pedneau, M.-H., Pic, É., Thompson, B., Veillette, M., Thaler, M., Scapino, I., Lebeuf, M., Baghdadi, M., Castillo Toro, A., Bélanger Cayouette, A., Dubois, M.-J., Durocher, A.F., Girard, S.B., Carranza Diaz, A.K., Khalloufi, A., Leclerc, S., Lemieux, J., Pérez Maldonado, M., Pilon, G., Murphy, C.P., Notling, C.A., Ofori-Darko, D., Provencher, J., Richer-Fortin, A., Turgeon, N., Duchaine, C., 2022. Antimicrobial resistance in the environment: Towards elucidating the roles of bioaerosols in transmission and detection of antibacterial resistance genes. <strong>Antibiotics</strong>, 11(7), 974. DOI: <a href="" target="_blank">10.3390/antibiotics11070974</a>.

Labbé, M., Thaler, M., Pitot, T.M., Rapp, J., Vincent, W.F., Culley, A.I., 2022. Climate-endangered arctic epishelf lake harbors viral assemblages with distinct genetic repertoires. <strong>Applied and Environmental Microbiology</strong>, 88(17), e00228-22. DOI: <a href="" target="_blank">10.1128/aem.00228-22</a>.

Marois, C., Girard, C., Klanten, Y., Vincent, W.F., Culley, A.I., Antoniades, D., 2022. Local habitat filtering shapes microbial community structure in four closely spaced lakes in the High Arctic. <strong>Frontiers in Microbiology</strong>, 13, 779505. DOI: <a href="" target="_blank">10.3389/fmicb.2022.779505</a>.

Zayed, A.A., Wainaina, J.M., Domínguez-Huerta, G., Pelletier, E., Guo, J., Mohssen, M., Tian, F., Adjie Pratama, A., Bolduc, B., Zablocki, O., Cronin, D., Solden, L., Delage, E., Alberti, A., Aury, J.-M., Carradec, Q., da Silva, C., Labadie, K., Poulain, J., Ruscheweyh, H.-J., Salazar, G., Shatoff, E., Tara Oceans Coordinators,., Bundschuh, R., Kubatko, L.S., Chaffron, S., Culley, A.I., Sunagawa, S., Kuhn, J.H., Wincker, P., Sullivan, M.B,, 2022. Cryptic and abundant marine viruses at the evolutionary origins of Earth’s RNA virome. <strong>Science</strong>, 376(6589): 156-162. DOI: <a href="" target="_blank">10.1126/science.abm5847</a>.

Bégin, P.N., Tanabe, Y., Kumagai, M., Culley, A.I., Paquette, M., Sarrazin, D., Uchida, M., Vincent, W.F., 2021. Extreme warming and regime shift toward amplified variability in a far northern lake. <strong>Limnology and Oceanography</strong>, 66(S1: Biogeochemistry and ecology across Arctic aquatic ecosystems in the face of change): S17-S29. DOI: <a href="" target="_blank">10.1002/lno.11546</a>.

Bégin, P.N., Tanabe, Y., Rautio, M., Wauthy, M., Laurion, I., Uchida, M., Culley, A.I., Vincent, W.F., 2021. Water column gradients beneath the summer ice of a High Arctic freshwater lake as indicators of sensitivity to climate change. <strong>Scientific Reports</strong>, 11, 2868. DOI: <a href="" target="_blank">10.1038/s41598-021-82234-z</a>.

Jungblut, A.D., Raymond, F., Dion, M.B., Moineau, S., Mohit, V., Nguyen, G.Q.H., Déraspe, M., Francovic‐Fontaine, E., Lovejoy, C., Culley, A.I., Corbeil, J., Vincent, W.F., 2021. Genomic diversity and CRISPR‐Cas systems in the cyanobacterium <i>Nostoc</i> in the High Arctic. <strong>Environmental Microbiology</strong>, 23(6 - Special Issue on Oxygen Minimum Zone Microbiology): 2955-2968. DOI: <a href="" target="_blank">10.1111/1462-2920.15481</a>.

Lang, A.S., Vlok, M., Culley, A.I., Suttle, C.A., Takao, Y., Tomaru, Y., ICTV Report Consortium, , 2021. ICTV virus taxonomy profile: Marnaviridae 2021. <strong>Journal of General Virology</strong>, 102(8), 001633. DOI: <a href="" target="_blank">10.1099/jgv.0.001633</a>.

Vigneron, A., Cruaud, P., Culley, A.I., Couture, R.-M., Lovejoy, C., Vincent, W.F., 2021. Genomic evidence for sulfur intermediates as new biogeochemical hubs in a model aquatic microbial ecosystem. <strong>Microbiome</strong>, 9, 46. DOI: <a href="" target="_blank">10.1186/s40168-021-00999-x</a>.

Bégin, P.N., Rautio, M., Tanabe, Y., Uchida, M., Culley, A.I., Vincent, W.F., 2020. The littoral zone of polar lakes: inshore-offshore contrasts in an ice-covered High Arctic lake. <strong>Arctic Science</strong>, 7(1): 158-181. DOI: <a href="" target="_blank">10.1139/AS-2020-0026</a>.

Cruaud, P., Vigneron, A., Fradette, M.-S., Dorea, C.C., Culley, A.I., Rodriguez, M.J., Charette, S.J., 2020. Annual bacterial community cycle in a seasonally ice‐covered river reflects environmental and climatic conditions. <strong>Limnology and Oceanography</strong>, 65(S1 - Special Issue: Linking Metagenomics to Aquatic Microbial Ecology and Biogeochemical Cycles): S21-S37. DOI: <a href="" target="_blank">10.1002/lno.11130</a>.

Girard, C., Langlois, V., Vigneron, A., Vincent, W.F., Culley, A.I., 2020. Seasonal regime shift in the viral communities of a permafrost thaw lake. <strong>Viruses</strong>, 12(11), 1204. DOI: <a href="" target="_blank">10.3390/v12111204</a>.

Labbé, M., Girard, C., Vincent, W.F., Culley, A.I., 2020. Extreme viral partitioning in a marine-derived High Arctic lake. <strong>mSphere</strong>, 5(3), e00334-20. DOI: <a href="" target="_blank">10.1128/mSphere.00334-20</a>.

Lévesque, A., Thaler, M., Labrie, S.J., Marois, C., Vincent, A.T., Lapointe, A.-M., Culley, A.I., 2020. Complete genome sequences for two <em>Myoviridae</em> strains infecting cyanobacteria in a subarctic lake. <strong>Microbiology Resource Announcements</strong>, 9(10), e01339-19. DOI: <a href="" target="_blank">10.1128/MRA.01339-19</a>.

Vigneron, A., Cruaud, P., Langlois, V., Lovejoy, C., Culley, A.I., Vincent, W.F., 2020. Ultra‐small and abundant: <em>Candidate phyla </em>radiation bacteria are potential catalysts of carbon transformation in a thermokarst lake ecosystem. <strong>Limnology and Oceanography Letters</strong>, 5(2): 212-220. DOI: <a href="" target="_blank">10.1002/lol2.10132</a>.

Cruaud, P., Vigneron, A., Fradette, M.-S., Dorea, C.C., Culley, A.I., Rodriguez, M.J., Charette, S.J., 2019. Annual protist community dynamics in a freshwater ecosystem undergoing contrasted climatic conditions: The Saint-Charles River (Canada). <strong>Frontiers in Microbiology</strong>, 10, 2359. DOI: <a href="" target="_blank">10.3389/fmicb.2019.02359</a>.

Culley, A.I., 2019. New insight into the virosphere via metaviromics. University of Hawaii at Manoa, Department of Microbiologyseminar series. Honolulu, Hawaï.

Culley, A.I., 2019. The wild viruses of the High Arctic. University of Hawaii at Manoa, Department of Oceanography seminar series. Honolulu, Hawaï.

Gregory, A.C., Zayed, A.A., Conceição-Neto, N., Temperton, B., Ardyna, M., Arkhipova, K., Carmichael, M., Cruaud, C., Dimier, C., Domínguez-Huerta, G., Ferland, J., Kandels, S., Liu, Y., Marec, C., Pesant, S., Picheral, M., Pisarev, S., Poulain, J., Tremblay, J.-É., Dean, V., Babin, M., Bowler, C., Culley, A.I., de Vargas, C., Dutilh, B.E., Iudicone, D., Karp-Boss, L., Roux, S., Sunagawa, S., Wincker, P., Sullivan, M.B., 2019. Marine DNA viral macro- and microdiversity from pole to pole. <strong>Cell</strong>, 177(5): 1109-1123. DOI: <a href="" target="_blank">10.1016/j.cell.2019.03.040</a>.

Lapointe, A.-M., Klanten, Y., Antoniades, D., Culley, A.I., 2019. Structure des communautés microbiennes dans les sédiments lacustres du Haut-Arctique. Journée de la recherche en sciences et en génie, Université Laval. Québec, Québec, Canada.

Lévesque, A., Vincent, W.F., Comte, J., Lovejoy, C., Culley, A.I., 2019. Chlorovirus and myovirus diversity in permafrost thaw ponds. <strong>Aquatic Microbial Ecology</strong>, 82(2): 209-224. DOI: <a href=" " target="_blank">10.3354/ame01893 </a>.

Vigneron, A., Lovejoy, C., Cruaud, P., Kalenitchenko, D., Culley, A.I., Vincent, W.F., 2019. Contrasting winter versus summer microbial communities and metabolic functions in a permafrost thaw lake. <strong>Frontiers in Microbiology</strong>, 10, 1656. DOI: <a href="" target="_blank">10.3389/fmicb.2019.01656</a>.

Brisebois, E., Veillette, M., Dion-Dupont, V., Lavoie, J., Corbeil, J., Culley, A.I., Duchaine, C., 2018. Human viral pathogens are pervasive in wastewater treatment center aerosols. <strong>Journal of Environmental Sciences</strong>, 67: 45-53. DOI: <a href="" target="_blank">10.1016/j.jes.2017.07.015</a>.

Comte, J., Culley, A.I., Lovejoy, C., Vincent, W.F., 2018. Microbial connectivity and sorting in a High Arctic watershed. <strong>ISME Journal</strong>, 12: 2988-3000. DOI: <a href="" target="_blank">10.1038/s41396-018-0236-4</a>.

Culley, A.I., 2018. New insight into the RNA aquatic virosphere via viromics. <strong>Virus Research</strong>, 244: 84-89. DOI: <a href="" target="_blank">10.1016/j.virusres.2017.11.008</a>.

Marois, C., Klanten, Y., Triglav, K., Antoniades, D., Culley, A.I., 2018. Diversity of microbial populations in Stuckberry Valley lakes (Nunavut, Canada) in a context of climate change. Journée de la Recherche en Sciences et Génie, Université Laval. Québec, Québec, Canada.

Vigneron, A., Cruaud, P., Mohit, V., Martineau, M.-J., Culley, A.I., Lovejoy, C., Vincent, W.F., 2018. Multiple strategies for light-harvesting, photoprotection, and carbon flow in high latitude microbial mats. <strong>Frontiers in Microbiology</strong>, 9, 2881. DOI: <a href="" target="_blank">10.3389/fmicb.2018.02881</a>.

Cruaud, P., Vigneron, A., Fradette, M.-S., Charette, S.J., Rodriguez, M.J., Dorea, C.C., Culley, A.I., 2017. Open the Sterivex<sup>TM</sup> casing: An easy and effective way to improve DNA extraction yields. <strong>Limnology and Oceanography: Methods</strong>, 15(12): 1015-1020. DOI: <a href="" target="_blank">10.1002/lom3.10221</a>.

Déraspe, M., Raymond, F., Boisvert, S., Culley, A.I., Roy, P.H., Laviolette, F., Corbeil, J., 2017. Phenetic comparison of prokaryotic genomes using k-mers. <strong>Molecular Biology and Evolution</strong>, 34(10): 2716-2729. DOI: <a href="" target="_blank">10.1093/molbev/msx200</a>.

Labbé, M., Vincent, W.F., Culley, A.I., 2017. Diversité et dynamiques des virus aquatiques du Haut-Arctique Canadien dans un contexte de changements climatiques. 1e réunion annuelle de Sentinelle Nord. Québec, Québec, Canada.

Marois, C., Culley, A.I., 2017. Dynamique hôte-cyanophage provenant du subarctique. Groupe de recherche en écologie buccale, Faculté de médecine dentaire, Université Laval. Québec, Québec, Canada.

Mohit, V., Culley, A.I., Lovejoy, C., Bouchard, F., Vincent, W.F., 2017. Hidden biofilms in a far northern lake and implications for the changing Arctic. <strong>npj Biofilms and Microbioms</strong>, 3: article no. 17. DOI: <a href="" target="_blank">10.1038/s41522-017-0024-3</a>.

Vincent, A.T., Derome, N., Boyle, B., Culley, A.I., Charette, S.J., 2017. Next-generation sequencing (NGS) in the microbiological world: How to make the most of your money. <strong>Journal of Microbiological Methods</strong>, 138: 60-71. DOI: <a href="" target="_blank">10.1016/j.mimet.2016.02.016</a>.

Comte, J., Culley, A.I., Lovejoy, C., Vincent, W.F., 2016. &Eacute;tude de l&rsquo;importance relative de la dispersion pour la diversit&eacute; des communaut&eacute;s microbiennes des &eacute;cosyst&egrave;mes aquatiques du Haut Arctique. Colloque du CEN 2016, Université du Québec à Trois-Rivières. Trois-Rivières, Québec, Canada.

Labbé, M., Culley, A.I., Vincent, W.F., 2016. Diversit&eacute; et dynamique des virus aquatiques du Grand Nord canadien dans un contexte de changements climatiques. Colloque du CEN 2016, Université du Québec à Trois-Rivières. Trois-Rivières, Québec, Canada.

Lévesque, A., Vincent, W.F., Culley, A.I., 2016. &Eacute;tude de la diversit&eacute; virale des mares de thermokarst subarctiques. Colloque du CEN 2016, Université du Québec à Trois-Rivières. Trois-Rivières, Québec, Canada.

Miranda, J.A., Culley, A.I., Schvarcz, C.R., Steward, G.F., 2016. RNA viruses as major contributors to antarctic virioplankton. <strong>Environmental Microbiology</strong>, 18(11 - Special Issue on Pathogen and Antibiotic Resistance Ecology): 3714–3727. DOI: <a href="" target="_blank">10.1111/1462-2920.13291</a>.

Trudel, M.V., Vincent, A.T., Attéré, S.A., Labbé, M., Derome, N., Culley, A.I., Charette, S.J., 2016. Diversity of antibiotic-resistance genes in Canadian isolates of <em>Aeromonas salmonicida</em> subsp. <em>salmonicida</em>: dominance of pSN254b and discovery of pAsa8. <strong>Scientific Reports</strong>, 6: 35617. DOI: <a href="" target="_blank">10.1038/srep35617</a>.

Culley, A.I., Shakya, M., Lang, A.S., 2015. Viral evolution at the limits. Pages 209-222 dans Microbial Evolution under Extreme Conditions. Life in Extreme Environments, De Gruyter.

Culley, A.I., 2014. A lot from a little: new insights in to the marine viral unknown. Université de Montréal, Département de sciences biologiques. Montréal, Québec, Canada.

Culley, A.I., Mueller, J.A., Belcaid, M., Wood-Charlson, E.M., Poisson, G., Steward, G.F., 2014. The characterization of RNA viruses in tropical seawater using targeted PCR and metagenomics. <strong>mBio</strong>, 5(3): e01210-14. DOI: <a href="" target="_blank">10.1128/mBio.01210-14</a>.

Mueller, J.A., Culley, A.I., Steward, G.F., 2014. Variables influencing extraction of nucleic acids from microbial plankton (viruses, bacteria, and protists) collected on nanoporous aluminum oxide filters. <strong>Applied and Environmental Microbiology</strong>, 80(13): 3930 –3942. DOI: <a href="" target="_blank">10.1128/AEM.00245-14</a>.

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